pentobarbital will decrease the level or result of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with strong CYP3A4 inducers may end up in lowered serum concentrations and loss of antimalarial efficacypentobarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absor